GHK-Cu Copper Peptide Serum with GHK-Cu + Hyaluronic Acid
GHK-Cu Copper Peptide Serum
1% GHK-Cu + Hyaluronic Acid · 60ml / 2.02oz
- ✔Replaces a peptide your skin makes less of every year
- ✔Firmer, smoother-looking skin over 8–12 weeks
- ✔Hydration you feel from the first morning
- ✔Gentle daily use — and no sun sensitivity, unlike retinol
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GHK-Cu Copper Glow Peptide Face Cream
Locks your serum in overnight. Same GHK-Cu peptide, richer form.

The two steps either side of your serum
Cleanse before it, seal after it. Both are cheaper added here than bought on their own.


Korean Matcha Hydrating Foam Cleanser
Copper peptides absorb better into properly cleansed skin. Lifts the day off without stripping your barrier.

GHK-Cu Copper Glow Peptide Face Cream
A rich overnight balm built on the same GHK-Cu peptide — it seals the serum in while you sleep.
Thirty seconds, morning and night

Cleanse
Wash and lightly pat skin, leaving it slightly damp so the serum has something to sink into.

Apply 3–4 drops
Press into face and neck until absorbed. Layers clear and never pills under makeup.

Seal it in
Follow with moisturiser. In the morning, finish with SPF.
Niacinamide · Ceramides · Hyaluronic Acid · Moisturiser · SPF
Vitamin C · AHAs & BHAs · Retinol
Patch test first. Skip it if you have a known copper allergy or Wilson’s disease, and check with your doctor if you’re pregnant or breastfeeding. External use only; avoid the eye area.
Questions, answered
How long does one bottle last?+
Is 1% a lot?+
Will it make me break out at first?+
Why is it blue?+
Is this better than retinol?+
Can I use it with vitamin C or retinol?+
Can I use it on my neck and chest?+
Is it safe for sensitive skin?+
What if it doesn’t work for me?+
Your body makes this peptide. By 60, it makes 60% less.
GHK-Cu isn’t something new being put into skincare. It’s something your own body runs out of.
Published figures for GHK levels in human blood plasma — a drop of more than 60% across four decades.
Isolated from human blood
Dr Loren Pickart identified GHK in human plasma and found it made aged tissue behave more like young tissue. Fifty years of study followed.
A published 12-week facial trial
A GHK-Cu cream was applied for 12 weeks to 71 women with sun-damaged skin, measuring skin density, thickness, laxity and fine lines.
Small enough to get through
Most actives are too large to cross the skin’s outer barrier. GHK-Cu is one of the few copper complexes small enough to — which is why it works topically at all.
Research described here concerns the GHK-Cu peptide itself, not this specific formulation. Zyntra has not conducted its own clinical trial. Individual results vary.
Three things you’ll actually notice
Skip the biochemistry. Here’s what changes, and roughly when.

Skin that bounces back
Copper peptides signal skin to build collagen and elastin — the two proteins behind that snap. It’s the slowest change, and the one people notice around week 8.

Texture you can feel
A calmer, more even-looking surface and softer-looking fine lines. Makeup stops catching and starts gliding.

Plump from the first morning
The hyaluronic acid does this immediately, long before the peptide’s slower work shows. It’s why the bottle feels worth it on night one.
Two ingredients. Here’s what each one is.
If you’ve never heard of either, that’s normal. Neither name tells you anything useful — so here’s the plain version.

GHK-Cu
What it is: a tiny protein fragment — just three amino acids — with a copper atom attached. Your body already makes it. It’s in your blood.
What it does: it acts as a signal. It tells skin cells to produce collagen and elastin, and helps clear out damaged collagen so newer fibres can replace it. That’s why the change is gradual rather than overnight.
Why it’s blue: the copper. Not a dye. It absorbs clear.
1% — the sweet spot, and printed on the label
Hyaluronic Acid
What it is: a moisture magnet. Your body makes this one too — it’s part of what keeps young skin looking plump.
What it does: it pulls water into the surface layers of your skin and holds it there — over a thousand times its own weight in water. That’s the instant plumpness, and it’s what stops a peptide serum feeling tight or dry.
Included — not a separate purchaseThese two aren’t just sharing a bottle — they work better together.
Laboratory and ex-vivo skin research on GHK-Cu paired with hyaluronic acid found the combination raised collagen IV production well beyond either ingredient on its own. Collagen IV sits at the junction between your skin’s upper and lower layers — the seam that keeps skin looking taut. The hyaluronic acid also creates the hydrated environment copper peptides absorb into best. Cell and ex-vivo skin research on the ingredient pairing, not a human trial of this product.
Copper peptides compound. Here’s the arc.
Not a one-week active. Consistency does the work — which is why one bottle covers a full cycle.
Instant hydration
Skin drinks it in and looks softer and plumper — that’s the hyaluronic acid working immediately.
1–2
Calmer, smoother
Skin feels smoother to the touch and looks less irritated. The tight, dry feeling eases off.
3–6
More even texture
Tone looks more even, texture more refined. Makeup glides instead of catching.
8–12
Firmer & more radiant
The payoff. Published research on the peptide puts visible firmness and fine-line change in this window.
Individual results vary. One 60 ml bottle is a 2-month supply at full use.
Some people get worse before better. Here’s why.
A minority of people get redness, small bumps or breakout-like activity in the first one to three weeks. It happens because GHK-Cu speeds up skin renewal, which brings existing congestion to the surface faster than usual. It typically settles within a few weeks.
The single biggest cause is going straight to twice a day from day one. So don’t. Here’s the way in:
- Weeks 1–2: 3 nights a week only.
- Weeks 3–4: every other night.
- Week 5 on: nightly, then add mornings if your skin is happy.
If it’s getting worse after six weeks rather than better, that’s not an adjustment period — stop and email us. We’d rather refund you than have you push through something that isn’t working.
Most people never experience this at all. We’d just rather you hear it from us than find out and assume something went wrong.
Give it 12 weeks.
That’s what the research says it takes — and one bottle covers the whole thing. From $18.33 a month.
↑ Choose your supply30-day money-back · Free shipping $50+ · Cruelty-freeThese statements describe the cosmetic appearance benefits of this product. This product is intended to improve the look of skin and does not alter its structure or function. Individual results may vary. Not evaluated by the FDA; not intended to diagnose, treat, cure or prevent any disease. For external use only; avoid the eye area and discontinue use if irritation occurs.
Ask about this serum
Answers written by the Zyntra team
Cosmetic information only — not medical advice. For anything health-related, speak to your doctor.