GHK-Cu Copper Peptide Serum with GHK-Cu + Hyaluronic Acid
Advanced care for healthy-looking skin: hydrates, improves firmness, rejuvenates
GHK-Cu Copper Peptide Serum with GHK-Cu + Hyaluronic Acid
Paraben-free, dermatologically tested, fragrance-free, cruelty-free copper peptide serum
Silky blue copper peptide serum texture swatch on fingertip
Core dual-effect ingredients: Copper Tripeptide-1 GHK-Cu and Sodium Hyaluronate
How copper tripeptide-1 GHK-Cu works across the skin cell layers
Copper peptide and hyaluronic acid dual-effect combination
Silky, dewy, non-sticky serum texture from the dropper
Lightweight serum absorbs quickly without clogging pores
Macro close-up of copper peptide serum dropper and blue drop
Woman holding a bottle of Zyntra GHK-Cu Copper Peptide Serum
Smiling woman holding Zyntra GHK-Cu Copper Peptide Serum
Three bottles of Zyntra GHK-Cu Copper Peptide Serum

Copper peptides + hyaluronic acid

GHK-Cu Copper Peptide Serum

$67.99$126.87Save 46%

2 bottles · $34.00 each

Lines look softer in 8 weeks. Skin looks firmer by week 12.

GHK-Cu is the copper peptide everyone is asking about. This is it as a serum you smooth on, no needles, paired with hyaluronic acid for plumper-looking skin from day one. Your skin makes GHK-Cu naturally, but less of it every year after your twenties, which is when crow’s feet, fine lines and lost bounce start to show.

  • GHK-Cu, studied in human skin for the look of fine lines and firmness
  • The blue is real copper, the sign of genuine GHK-Cu. No dye.
  • No needles, no downtime. A few drops morning and night. Fragrance-free.
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Sound familiar?

The changes that start after 30

A woman checking the lines at the corner of her eye in the bathroom mirror
  • Fine lines at the corner of an eye
    Crow’s feet that stay after you stop smilingLines around the eyes look softer in 8 weeks
  • Fingers pressing along the jaw
    Skin that doesn’t bounce back like it used toFirmer, bouncier-looking skin by week 12
  • Tired-looking skin in a bathroom mirror
    Dull, dry skin that makes you look tiredPlumper, dewier-looking skin from day one

One serum for all three. Copper peptides (GHK-Cu) and hyaluronic acid. A few drops, morning and night.

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Your questions, answered

When will I see results?
Skin looks plumper and dewier from the first day. Fine lines look softer around week 8, and skin looks firmer by week 12 of daily use. Everyone’s skin is different.
How do I use it?
Morning and night on clean, dry skin. Smooth a few drops over your face and neck. For crow’s feet, pat two drops along the bone around the eye with your ring finger, not on the eyelid. Follow with moisturizer, and sunscreen in the morning.
Can I use it with retinol or vitamin C?
Yes. Use vitamin C in the morning and this serum at night. If you use retinol, alternate nights: serum one night, retinol the next.
Is it OK for sensitive skin?
It’s fragrance-free and paraben-free. If your skin is sensitive, patch test first and start every other night for two weeks. Skip it if you have a known copper allergy, and check with your doctor if you’re pregnant or breastfeeding.
How long does one bottle last?
About a month, used morning and night (60 ml). That’s why Auto-Refill ships 1 bottle every month, 2 every 2 months, or 3 every 3 months. Skip or cancel anytime.
  • The serum is velvety smooth and calming to my skin. No stinging or peeling of any type. I’ve been using it about 10 days and I am seeing the beginning of what seems like rested skin. Will know more soon. Thank you!Jennifer T., verified buyer
How does Auto-Refill work?

You pick how often it ships. You are only charged when a refill ships.

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Shipping and returns

Ships in 1–3 business days. 30 days, money back, no forms: email support with your order number.

What changes after 30

What changes after 30

Lines from smiling and squinting start to stay. Skin holds less water, so it looks flatter and duller. And it takes longer to bounce back.

This serum is made for exactly that: copper peptides (GHK-Cu) and hyaluronic acid in one bottle.

Up close

The copper peptide in every drop

What you’re seeing: an illustration of GHK-Cu, the copper peptide in this serum, on skin. Each molecule is three amino acids holding one copper ion.

  • Why it’s blue. The copper in GHK-Cu gives the serum its color. No dye is added.
  • Why after 30. Your body makes GHK-Cu naturally, and makes less of it every year after your twenties.
How does it work?

How does it work?

Two ingredients, working at two speeds.

1Hyaluronic acid: from day onePulls water into the top layers of skin, so it looks plumper and smoother from the first morning.
2GHK-Cu: week by weekUsed morning and night, it’s the peptide studied for the look of fine lines at 8 weeks and firmness at 12.

What’s inside, and why your skin will love it

GHK-Cu (copper tripeptide-1)

The peptide studied in human skin for the look of fine lines and firmness.

Hyaluronic acid

Pulls water into the skin for plumpness from day one.

Silky, non-sticky texture

Silky, non-sticky texture

Absorbs fast and sits well under moisturizer and makeup.

Nothing you don’t need

Nothing you don’t need

Fragrance-free, paraben-free, vegan, cruelty-free.

Benefits that build over time

What changes, and roughly when.

  1. Day 1

    Plump, hydrated skin

    The hyaluronic acid works immediately.

    Plump, hydrated skin
  2. Weeks 3–6

    Smoother texture

    A calmer, more even-looking surface and softer-looking fine lines.

    Smoother texture
  3. Weeks 6–12

    Skin that bounces back

    The slowest change. Give it 8 to 12 weeks of daily use.

    Skin that bounces back

Why Zyntra?

Zyntra serumTypical copper serum
Bottle size60 ml15–30 ml
Hyaluronic acid in the same dropVaries
Fragrance-freeVaries
Vegan and cruelty-freeVaries
Auto-Refill, skip or cancel anytime

Sizes checked Oct 2026: The Ordinary Multi-Peptide + Copper Peptides 1% and Naturium Multi-Peptide Advanced Serum, 30 ml; NIOD Copper Amino Isolate Serum, 15 or 30 ml.

Frequently asked questions

Will it make me break out at first?

It can for some people in the first one to three weeks. Start every other night for the first two weeks. If it is still getting worse after six weeks, stop and email us.

Why is it blue?

The blue is the copper bound inside GHK-Cu itself, not an added dye. It absorbs clear.

Is this better than retinol?

Different tools. Copper peptides are gentle enough to use every day, morning and night. Plenty of people use both, on alternate nights.

How does Auto-Refill work?

You get 20% off every order and choose how often it ships. You’re only charged when a refill ships. Skip, pause, change frequency or cancel anytime.

What if it doesn’t work for me?

Email us within 30 days with your order number for a full refund. No forms.